Two ES cell-derived optic cup formed by self-organization in 3D culture. Green color is fluorescence of GFP protein that was engineered to mark retinal tissue.Image: M. Eiraku and Y.Sasai at RIKEN Center for Developmental Biology
By a GenomeWeb staff reporter
Non-profit firm Diagnostics for All today said it has received a two-year, $3 million grant from the Bill and Melinda Gates Foundation and the UK’s Department for International Development to develop inexpensive agriculture diagnostic tests for livestock health and other purposes in sub-Saharan Africa.
The several tests will be designed to identify milk spoilage, cows with infections and determine when cows are in heat or pregnant.
Another test will to identify aflatoxin, a potent hepatocarcinogen found in grain mold.
The new effort comes as many large drug makers, unable to find enough new drugs, are paring back research. Promising discoveries in illnesses like depression and Parkinson’s that once would have led to clinical trials are instead going unexplored because companies have neither the will nor the resources to undertake the effort.
via www.nytimes.com
The story of the fraudulent paper showing a link between the MMR vaccine and autism continues to unfold. The British Medical Journal, which originally published the paper by disgraced researcher, Andrew Wakefield, only to later retract it, now reports that Wakefield had devised a scheme to make a substantial profit from the scare that he correctly anticipated would arise from the paper. Steven Clark University of Wisconsin
The BMJ reports that Wakefield planned, even before the study was finished, to profit from selling diagnostic tests and by making his own, "safer" vaccine. Steven Clark University of Wisconsin
Wakefield, a medical doctor, has been banned from practicing medicine in Great Britain. Steven Clark University of Wisconsin
via www.bmj.com
In order to make a better biofactory, University of Wisconsin Genetics Professor Frederick R. Blattner and his colleagues developed Clean genome® E. coli, an engineered bug from which all mobile genetic elements have been deleted. DNA segments resembling toxin genes or virulence factor genes were also removed from the Clean Genome E. coli, heading off other potential complications. Steven S. Clark
Dr Blattner founded Scarab Genomics LLC in 2002 to commercialize Clean Genome E. coli. In addition to the elimination of problems caused by mobile elements, the slimmer, trimmer Clean Genome strain is more efficient at manufacturing engineered proteins and DNA. Moreover, as a simpler organism, it is better suited to genetic engineering research. Steven S. Clark
In some good fiscal news yesterday for the U.S. science community, a Senate spending panel has crafted a 2011 federal budget that would give several science agencies increases that are close to their requested levels. But lobbyists say that it's too soon to celebrate. Read more at ScienceInsider.
So, Senator Tom Coburn (R-OK) is trying to block the SBIR contintuing resolution.....again! Read more below from the SBIR Coach.
Stem cells taken from the brain of a 13-year-old girl were transplanted into newborn mice and developed into a variety of brain cells almost identical to the animals' own — a procedure that someday could be used to replace the misfiring cells in some epilepsy patients, the researchers said.
NIH Guide for Grants and Contracts
October 22, 2010
Table of Contents (TOC)
Follow a scientist with a PhD in Immunology who has studied how immune cells recognize viruses, including influenza. He is a recently retired medical school professor and here, shares news and his opinions on the COVID-19 pandemic..
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